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Obtain highly sensitive super-resolution with the RCM1

While requiring only 85 nano-watts of laser power to get a clear image

The RCM1 system enables you to study your live cells in super-resolution while keeping the laser power very low. It is a highly sensitive system, meaning that it can focus on the cells you are studying while removing background noise and reducing unwanted blur. Next to this, the RCM1 captures high-resolution imaging which makes sure you won’t lose any valuable data of your samples.

The RCM1 system is based on the Re-scan Confocal Microscope (RCM) principle. This is where the RCM1 draws its powers from. In this principle, the image gets optically re-scanned within the RCM1 module and projects the image directly on a CCD or sCMOS camera. The results in a high resolution and highly sensitive imaging, which is exceptionally suitable for challenging biological applications where for example the signal is limited.

With the RCM1 module attached to your widefield microscope, you can capture datasets with 170nm raw resolution (120nm after deconvolution) by using 60x to 100x high numerical aperture (NA) magnification objectives.

You also don’t need a high laser power, because the RCM1 acquires super-resolution images with only 85 nano-watts of laser power. This will result in low phototoxicity of your cells.

The RCM1 also has a NIR version. This version allows you to obtain deep tissue biomedical imaging, which is achieved because of the much higher sensitivity in the near-infrared wavelengths than other systems on the market. The RCM1 can operate on 640nm and 785nm wavelengths and because these wavelengths are much longer, this will result in even less phototoxicity of your samples. This all while you can penetrate your biological samples much better.

The RCM1 System is very easy to use and user-friendly. It requires little setup time and integrates seamlessly into most widefield microscopes and 3rd party software.

Image by Stan Hilt

Product features

Super-resolution images

With the RCM1 you can take stunning super-resolution images of your samples.

High sensitivity

With its high sensitivity, you can have the image focus on your samples and get rid of unnecessary image-pollution

Easy addon

The CRM1 is an easy addon to existing wide-field microscopes. Turn your already existing microscope into a super microscope and capture even more valuable information.

User Friendly

Easily operatable by a laboratory professor or student and also easily integrates into 3rd party software.

  • Detector Camera
  • Resolution 120 nm **
  • Sensitivity up to 95% QE
  • FOV 130×130 um (60x, super-resolution)
  • Optimized for 100x, 60x (high NA)
  • Scanner Analog (open-loop)
  • Speed 1fps @ 512 x 512 pixels
  • Wavelength VIS or NIR
  • Software Micromanager, NIS Elements, Volocity
  • Integration API
  • PSF for deconvolution with Microvolution, SVI Huygens
  • Bypass mode Yes

Satisfied customers

That's why we do it!

"We choose NBS Scientific because they offer a good price-quality ratio, with user-oriented solutions. NBS Scientific is a friendly and practical supplier."

"At NBS Scientific I got quick and reliable responses to questions and appointments. All advice and attention was expertly given. We've been happily working together for over 2 years now. "

I experience NBS Scientific as an excellent partner with pleasant employees. I have good contact with them.

"We chose NBS Scientific because we were impressed by the quality of Micronic products that are offered for a fair price. We experienced high commitment from NBS Scientific to enable the interaction of Micronic tubes with a third party device. We appreciate NBS Scientific for the reliability, good customer service and great engagement."


Need more information about the RCM1?

Don't hesitate to contact us

Wish to know more about the RCM1? Wish to have a demonstration? Feel free to contact us today!

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