RCM1

The RCM1 system enables you to study your live cells in high-resolution while keeping the laser power very low. It is a highly sensitive system, meaning that it can focus on the cells you are studying while removing background noise and reducing unwanted blur.

The RCM1 system is based on the Re-scan Confocal Microscope (RCM) principle. This is where the RCM1 draws its powers from. RCM combines the optics of a standard confocal microscope with an extra rescanning unit. The scanner reads the sample on the x and y-axis and the re-scanner writes the image on the detector. In our systems we use CMOs detectors which allows us to get up to 95% QE. This results in high resolution and high sensitivity imaging, which is exceptionally suitable for life cell imaging or when low signal levels are present.

With the RCM1 module attached to your widefield microscope, you can capture datasets with 170nm raw resolution (120nm after deconvolution) by using 60x to 100x high numerical aperture (NA) magnification objectives.

You also don’t need a high laser power, because the RCM1 acquires super-resolution images with only 85 nano-watts of laser power. This will result in low phototoxicity of your cells.

The RCM1 also has a NIR version. This version is perfect for deep tissue imaging because lateral resolution is also improved at 785nm. The RCM1 can operate on 640nm and 785nm wavelengths and because these wavelengths are of lower energy, this will result in even less phototoxicity of your samples. In addition, with these wavelengths you can take advantage of diminished autofluorescence and light attenuation, which allows you to penetrate deeper into your samples much better.

The RCM1 System is very easy to use and user-friendly. It requires little setup time and integrates seamlessly into most widefield microscopes and 3rd party software.

Image by Stan Hilt Confocal.nl