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Obtain highly sensitive super-resolution with the RCM1

While requiring only 85 nano-watts of laser power to get a clear image

1 fps @ 512 x 512 pixels
170 nm and 500 nm axial resolution
130×130 micrometers (60x, super-resolution) FOV
up to 95% QE sensitvity

The RCM1 system enables you to study your live cells in high-resolution while keeping the laser power very low. It is a highly sensitive system, meaning that it can focus on the cells you are studying while removing background noise and reducing unwanted blur.

The RCM1 system is based on the Re-scan Confocal Microscope (RCM) principle. This is where the RCM1 draws its powers from. RCM combines the optics of a standard confocal microscope with an extra rescanning unit. The scanner reads the sample on the x and y-axis and the re-scanner writes the image on the detector. In our systems we use CMOs detectors which allows us to get up to 95% QE. This results in high resolution and high sensitivity imaging, which is exceptionally suitable for life cell imaging or when low signal levels are present.

With the RCM1 module attached to your widefield microscope, you can capture datasets with 170nm raw resolution (120nm after deconvolution) by using 60x to 100x high numerical aperture (NA) magnification objectives.

You also don’t need a high laser power, because the RCM1 acquires super-resolution images with only 85 nano-watts of laser power. This will result in low phototoxicity of your cells.

The RCM1 also has a NIR version. This version is perfect for deep tissue imaging because lateral resolution is also improved at 785nm. The RCM1 can operate on 640nm and 785nm wavelengths and because these wavelengths are of lower energy, this will result in even less phototoxicity of your samples. In addition, with these wavelengths you can take advantage of diminished autofluorescence and light attenuation, which allows you to penetrate deeper into your samples much better.

The RCM1 System is very easy to use and user-friendly. It requires little setup time and integrates seamlessly into most widefield microscopes and 3rd party software.

Image by Stan Hilt

Product features

Super-resolution images

With the RCM1 you can take stunning super-resolution images of your samples

High sensitivity

The high sensitivity detectors allow using low laser power to prevent phototoxicity and bleaching


RCM1 is an easy to use add-on to any existing widefield microscope. Turn your already existing microscope into a super-resolution confocal version and capture even more valuable information

User Friendly

Easily operatable by a laboratory professor or student and also easily integrates into 3rd party software

  • Detector Camera
  • Resolution 170nm (lateral) and 500nm axial @ 488 nm
  • Sensitivity up to 95% QE (high sensitivity to prevent phototoxicity)
  • FOV 130×130 μm (60x, super-resolution)
  • Optimized for Low 10x-40x magnification and for high 40x-100x magnification
  • Scanner Analog (open-loop)
  • Speed 1fps @ 512 x 512 pixels
  • Wavelength VIS or NIR
  • Software Micromanager and 3rd party softwares such as NIS Elements, Volocity
  • Integration API
  • PSF for deconvolution with Microvolution, SVI Huygens
  • Bypass mode Yes
  • Beam splitter Dichroic quad band 405, 488, 561, 638
  • Add-on Wide range of widefield microscopes, inverted or upright

Satisfied customers

That's why we do it!

"We choose NBS Scientific because they offer a good price-quality ratio, with user-oriented solutions. NBS Scientific is a friendly and practical supplier."

"At NBS Scientific I got quick and reliable responses to questions and appointments. All advice and attention was expertly given. We've been happily working together for over 2 years now. "

I experience NBS Scientific as an excellent partner with pleasant employees. I have good contact with them.

"We chose NBS Scientific because we were impressed by the quality of Micronic products that are offered for a fair price. We experienced high commitment from NBS Scientific to enable the interaction of Micronic tubes with a third party device. We appreciate NBS Scientific for the reliability, good customer service and great engagement."


Need more information about the RCM1?

Don't hesitate to contact us

Wish to know more about the RCM1? Wish to have a demonstration? Feel free to contact us today!

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